Ziyuglycoside
Aller à la navigation
Aller à la recherche
Nom de la substance
Ziyuglycoside, ziyu-glycoside
Famille moléculaire
Source végétale
Propriétés
- Propriétés anticancéreuses [1], [2], inhibition de l'angiogenèse [3], [4], [5], [6], [7] (ziyuglycoside II)
Effet thérapeutique
Effets indésirables
Bibliographie
- ↑ Mimaki Y, Fukushima M, Yokosuka A, Sashida Y, Furuya S, Sakagami H. Triterpene glycosides from the roots of Sanguisorba officinalis. Phytochemistry. 2001 Jul;57(5):773-9. PMID 11397447
- ↑ Jang E, Inn KS, Jang YP, Lee KT, Lee JH. Phytotherapeutic Activities of Sanguisorba officinalis and its Chemical Constituents: A Review. Am J Chin Med. 2018;46(2):299-318. doi: 10.1142/S0192415X18500155. PMID 29433389.
- ↑ Nam SH, Lkhagvasuren K, Seo HW, Kim JK. Antiangiogenic Effects of Ziyuglycoside II, a Major Active Compound of Sanguisorba officinalis L. Phytother Res. 2017 Sep;31(9):1449-1456. doi: 10.1002/ptr.5874. PMID 28718964.
- ↑ Zhu AK, Zhou H, Xia JZ, Jin HC, Wang K, Yan J, Zuo JB, Zhu X, Shan T. Ziyuglycoside II-induced apoptosis in human gastric carcinoma BGC-823 cells by regulating Bax/Bcl-2 expression and activating caspase-3 pathway. Braz J Med Biol Res. 2013 Aug;46(8):670-5. doi: 10.1590/1414-431X20133050. PMID 23969976; PMCID: PMC3854423.
- ↑ Zhu X, Wang K, Zhang K, Huang B, Zhang J, Zhang Y, Zhu L, Zhou B, Zhou F. Ziyuglycoside II inhibits the growth of human breast carcinoma MDA-MB-435 cells via cell cycle arrest and induction of apoptosis through the mitochondria dependent pathway. Int J Mol Sci. 2013 Sep 3;14(9):18041-55. doi: 10.3390/ijms140918041. PMID 24005866.
- ↑ Zhu X, Wang K, Zhang K, Zhu L, Zhou F. Ziyuglycoside II induces cell cycle arrest and apoptosis through activation of ROS/JNK pathway in human breast cancer cells. Toxicol Lett. 2014 May 16;227(1):65-73. doi: 10.1016/j.toxlet.2014.03.015. PMID 24680927
- ↑ Lkhagvasuren K, Kim JK. Ziyuglycoside II induces caspases-dependent and caspases-independent apoptosis in human colon cancer cells. Toxicol In Vitro. 2019 Sep;59:255-262. doi: 10.1016/j.tiv.2019.04.028. PMID 31029785